Annals of Saudi Medicine
Publication of the King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia
Users Online: 14 Home Print this page Email this page Small font sizeDefault font sizeIncrease font size
Home  About us   Issues     Search     Subscribe   Contact    Login 
Year : 2010  |  Volume : 30  |  Issue : 1  |  Page : 15-17

Mother-to-child transmission of HIV: Experience at a referral hospital in Saudi Arabia

 Section of Infectious Diseases, Department of Medicine, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia

Correspondence Address:
Abdulrahman A Alrajhi
Department of Medicine, King Faisal Specialist Hospital and Research Centre, MBC 46, PO Box 3354, Riyadh 11211
Saudi Arabia
Login to access the Email id
DOI: 10.4103/0256-4947.59367

PMID: 20103953

Get Permissions

Background and Objectives : The rate of mother-to-child transmission of human immunodeficiency virus (HIV) type 1 has been reported to be high in Saudi Arabia. We report the rate of such transmission among a cohort of HIV-infected women enrolled in an HIV program at a tertiary care facility in Riyadh. Methods : All HIV-infected women who became pregnant and delivered during their follow-up between January 1994 and June 2006 were included in this study. HIV viral load and CD4+ T-lymphocyte count near-term, the mode of delivery, and the HIV status of the newborn at 18 months were recorded. All women were counseled and managed according to the three-step PACTG 076 protocol. Results : Of 68 HIV-infected women in the cohort, 31 had 40 pregnancies; one aborted at 13 weeks gestation. The mode of delivery was elective cesarean delivery in 28 pregnancies (70%) at 36 weeks gestation, and 11 (27.5%) had normal spontaneous vaginal delivery. The median CD4+ T-lymphocyte count near-term was 536 cells per cubic millimeter and the median viral load for 25 pregnancies was 1646 copies/mL, with only nine pregnancies (22.5%) having viral loads of more than 1000 copies/mL. Fourteen pregnancies (35%) had undetectable HIV prior to delivery. All patients were taking antiretroviral therapy during pregnancy and delivery. All 39 newborns tested negative for HIV infection at the age of 18 months; none of the newborns was breastfed. Conclusions : Contrary to previous local experience, diagnosis, management, and antiretroviral therapy almost eliminated mother-to-child transmission of HIV-1 in our patient population.

Print this article     Email this article
 Next Article
 Previous Article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search Google Scholar for
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded126    
    Comments [Add]    

Recommend this journal